Meridol toothpaste is particularly effective for people who experience gum problems. The unique combination of amine fluoride and stannous fluoride has demonstrated its anti-plaque and anti-inflammatory, soothing properties in more than 100 clinical trials. Meridol toothpaste inactivates residual plaque and permanently inhibits new plaque formation. This then promotes the regeneration of irritated gums. It also contains flouride which provides effective caries protection. Fun fact: Meridol's history goes back to a small pharmacy in Basel, Switzerland, that was founded in 1683 and can still be found today!